I-IVEN ihlinzeka amakhasimende e-biopharmaceutical ngohlu olugcwele lwamathangi okuvutshelwa kwesiko le-microbial kusukela ocwaningweni nokuthuthukiswa kwelabhorethri, uvivinyo lokuhlola ukukhiqizwa kwezimboni, futhi inikeza izixazululo zobunjiniyela ezenziwe ngokwezifiso. Ukuklanywa nokukhiqizwa kwamathangi okuvutshelwa kulandela ngokuqinile imithetho ye-GMP kanye nezidingo ze-ASME-BPE, futhi kwamukele umklamo ochwepheshile, osebenziseka kalula kanye nemodular, futhi ingahlinzeka ngeziqukathi ezihlangabezana namazinga ahlukene emikhumbi yokucindezela kazwelonke njenge-ASME-U, GB150, ne-PED. Umthamo wethangi esingawuhlinzeka usukela kumalitha angu-5 kuya ku-30 ​​kilolitha, ongahlangabezana nezidingo zamagciwane aphezulu e-aerobic afana ne-Escherichia coli ne-Pichia pastoris. Lo mkhiqizo ulungele ukutshalwa kweqoqo lama-microorganisms esikalini sokuhlola kanye nokukhiqizwa kwemithi yebhayoloji njengemithi ye-recombinant protein (njenge-insulin) kanye nemigomo (njenge-HPV, umgomo we-pneumococcal).