Embonini yanamuhla yomhlaba wonke yemithi ethuthuka ngokushesha, ukwelashwa nge-intravenous infusion (IV), njengesixhumanisi esibalulekile emithini yokwelapha, kubeke amazinga aphezulu angakaze abonwe okuphepha kwezidakamizwa, ukuzinza, kanye nokusebenza kahle kokukhiqiza. I-Multi Chamber IV Bag, enomklamo wayo oyingqayizivele, ingakwazi ukuzuza ukuxutshwa kwezidakamizwa nezincibilikisi ngokushesha, ithuthukise kakhulu ukunemba kwemithi kanye nokuba lula. Sekuyifomu lokupakisha elikhethwayo lamalungiselelo ayinkimbinkimbi njengokudla okunomsoco, izidakamizwa ze-chemotherapy, ama-antibiotics, njll. Kodwa-ke, ukukhiqizwa kwemikhiqizo enjalo kudinga izimfuneko eziqinile kakhulu zobuchwepheshe bemishini, indawo ehlanzekile, nokuthobela. Abahlinzeki besevisi yobunjiniyela kuphela abaneqoqo elijulile lobuchwepheshe nolwazi lwephrojekthi yomhlaba wonke abanganikeza izixazululo ezithembeke ngempela.

Njengomholi wamazwe ngamazwe emkhakheni wobunjiniyela bezokwelapha, i-IVEN Pharmatech Engineering, enolwazi olungaphezu kweminyaka engama-30 embonini yezemithi, izibophezele ekuhlinzekeni amakhasimende omhlaba wonke ngezinsizakalo zobunjiniyela be-turnkey eyodwa-stop kusuka ekwakhiweni kwenqubo, ukuhlanganiswa kwemishini kuya ekutholeni isitifiketi sokuhambisana. EyethuI-Multi Chamber IV Bag Production Lineayigcini nje ngokuhlanganisa ubuchwepheshe bokuzenzakalela obusezingeni eliphezulu, kodwa futhi inenzuzo ewumgogodla yokuhambisana nemithetho yamazwe ngamazwe engu-100% njenge-EU GMP kanye ne-US FDA cGMP, isiza izinkampani ezithaka imithi ukuthi zenze imikhiqizo enenani eliphezulu futhi zibambe amathuba ezimakethe zomhlaba.

I-Multi Chamber IV Bag Intelligent Production Line: Ukuchaza Kabusha Umngcele phakathi Kokusebenza Kahle Nokuphepha

Ulayini wokukhiqiza wesikhwama sokufakwa we-VEN's chamber multi chamber uklanyelwe ukuhlangabezana nezinselele zokukhiqiza ukwakheka okuyinkimbinkimbi. Ngokusebenzisa amaqoqo amane obuchwepheshe obusha, kusiza amakhasimende ukuthi agqashule ekuvimbeleni ukukhiqiza okuvamile:

1. Multi chamber synchronous molding kanye nobuchwepheshe bokugcwalisa obunembile
Izikhwama zegumbi elilodwa lendabuko zithembele ezinyathelweni zokuxutshwa zangaphandle, ezibeka engcupheni yokungcola futhi zingasebenzi kahle. I-IVEN yamukela inqubo yefilimu enezingqimba eziningi co extruded izinto ezintathu-ntathu ze-thermoforming. Ngokubumba okunembayo okuphezulu nokulawulwa kwe-gradient yokushisa, amakamelo azimele angu-2-4 angakhiwa ngesitembu esisodwa, ngamandla okuhlukanisa angaphezu kuka-50N/15mm phakathi kwamakamelo, okuqinisekisa ukuvuza okungu-zero ngesikhathi sokuthutha nokugcinwa. Inqubo yokugcwalisa yethula iphampu yokugcwalisa eneziteshi eziningi eshayelwa yi-magnetic levitation linear motor, enobuncane bokunemba bokugcwalisa obungu-± 0.5%, esekela ukulungiswa okubanzi ukusuka ku-1mL kuye ku-5000mL, evumelana ngokuphelele nezidingo zokupakishwa koketshezi oluhlukile lwe-viscosity njengezixazululo zezakhi kanye nezidakamizwa ze-chemotherapy.

2. Uhlelo lokuxhuma oluyinyumba oluvalwe ngokugcwele
Ukuze kuxazululwe inkinga yokulawulwa kwe-microbial ezikhwameni eziningi ezixutshwe ngaphambili, i-VENN ithuthukise idivayisi enegunya lobunikazi ye-SafeLink ™ Aseptic activation. Idivayisi isebenzisa idizayini ye-laser yangaphambi kokusika eyenza buthakathaka isendlalelo, ehlanganiswe nemishini yokucupha ingcindezi. Izisebenzi zezokwelapha zidinga kuphela ukumpintsha ngesandla esisodwa ukuze zithole ukuxhumana okungenanyumba phakathi kwamagumbi, zigwema ingozi yemfucumfucu yengilazi engase ikhiqizwe amavalvu agoqayo avamile. Ngemuva kokuqinisekiswa kwenkampani yangaphandle, ukusebenza kokuvala kokuxhumeka okucushiwe kuhlangabezana nezinga le-ASTM F2338-09, futhi amathuba okuhlasela kwe-microbial angaphansi kuka-10 ⁻⁶.

3. Ukuhlola okubonwayo kobuhlakani bokwenziwa kanye nohlelo lokulandeleka
Ulayini wokukhiqiza uhlanganisa isistimu yokutholwa kwemodi ekabili ye-AI X-ray, ethola ngokuhambisanayo ukonakala kwefilimu, ukugcwalisa ukuchezuka kwezinga le-liquid, nobuqotho bokuvalwa kwegumbi ngamakhamera e-CCD anesinqumo esiphezulu kanye ne-micro focus X-ray imaging. Ama-algorithms okufunda okujulile angakwazi ukuhlonza ngokuzenzakalelayo amaphutha embobo ezingeni elingu-0.1mm, ngezinga lokutholwa okungamanga elingaphansi kuka-0.01%. Ngasikhathi sinye, isikhwama ngasinye sokufakwa sifakwa ne-chip ye-RFID ukuze kutholakale ukulandeleka okugcwele kusuka kumaqoqo wezinto ezingavuthiwe, imingcele yokukhiqiza kuya kumazinga okushisa okujikeleza, okuhlangabezana nezimfuneko zokwenziwa kwe-serial ze-FDA DSCSA (Drug Supply Chain Safety Act).

4. Isixazululo esiqhubekayo sokuvala inzalo ukonga amandla
Ikhabethe lendabuko lokuvala inzalo lesikhashana linamaphuzu ezinhlungu zokusetshenziswa kwamandla aphezulu kanye nomjikelezo omude. I-IVEN kanye nozakwethu baseJalimane ngokuhlanganyela bathuthukise uhlelo lwe-Rotary Steam in Place (SIP), olwamukela umklamo ozungezayo wombhoshongo wesifutho ukuze udale isiphithiphithi egumbini lesitimu esishisa kakhulu. Ingaqeda ukuvala inzalo kungakapheli imizuzu eyi-15 ku-121 ℃, yonga amandla angama-35% uma kuqhathaniswa nezindlela zendabuko. Isistimu ifakwe isilawuli esizithuthukisele sona se-B&R PLC, esingarekhoda futhi sigcine idatha yokusabalalisa okushisayo kweqoqo ngalinye (inani le-F ₀ ≥ 15), futhi likhiqize ngokuzenzakalelayo amarekhodi enqwaba kagesi athobela 21 CFR Ingxenye 11.

Ukuzibophezela kuka-VEN: inethiwekhi yesevisi yomhlaba wonke egxile empumelelweni yamakhasimende

Sazi kahle ukuthi imishini yezinga lokuqala idinga ukufaniswa nensizakalo yezinga lokuqala.I-VEN isungule izikhungo zobuchwepheshe emazweni angu-12 emhlabeni wonke, ihlinzeka nge-7 × 24-hora yokuxilongwa okukude kanye nokusekelwa kwempendulo yamahora angu-48 esizeni. Ithimba lethu lingahlinzeka ngezinsizakalo ezenziwe ngokwezifiso zangemuva kokuthengisa ngokusekelwe kumehluko wemithetho ezifundeni ezihlukene.

Esikhathini somuthi onembayo kanye nemithi yomuntu siqu, izikhwama zokufakwa emthanjeni zamagumbi amaningi zihlela kabusha imingcele yokwelashwa komzali. I-IVEN Pharmatech Engineering yakha ibhuloho eliya ekusaseni lezinkampani ezenza imithi emhlabeni wonke ngobungcweti bayo obuvelele bonjiniyela kanye nokuphishekela ukuthobela imithetho. Kungakhathaliseki ukuthi amaphrojekthi amasha noma ukuthuthukiswa kwamandla, umugqa wethu wokukhiqiza ohlakaniphile uzoba uzakwethu othembeke kakhulu.

Xhumana ne-VENithimba lochwepheshe ngokushesha lezixazululo ezenziwe ngezifiso kanye nezindaba zempumelelo zomhlaba wonke!