Emikhakheni ye-biotechnology kanye nama-biopharmaceutical, amagama athi "bioreactor" kanye ne- "bioferment" ajwayele ukusetshenziswa ngokushintshana, kepha abhekisela ezinhlelweni ezahlukahlukene ezinemisebenzi ethile kanye nezicelo. Ukuqonda umehluko phakathi kwalezi zinhlobo ezimbili zemishini kubalulekile kochwepheshe emkhakheni, ikakhulukazi lapho ukuklama nokwakha amasistimu ahlangabezana namazinga aqinile alawulwayo.

Ukuchaza imigomo

I-Bioreactor yigama elibanzi elimboza noma yisiphi isitsha lapho ukusabela okuphilayo kwenzeka. Lokhu kungafaka izinqubo ezihlukile njengokuvutshelwa, amasiko weseli, nokusabela kwe-enzyme. Ama-bioreactors angenzelwe izimo ze-aerobic noma ze-anaerobic futhi angeseka izinhlobo eziningi zezinto eziphilayo, kufaka phakathi amagciwane, imvubelo namaseli e-mairmalia. Bahlome ngokushisa okuhlukahlukene, ph, izinga le-oxygen, kanye nokulawulwa kokuphazamiseka ukwenza ngcono izimo zokukhula ze-microorganisms noma amaseli.

Ngakolunye uhlangothi, i-biofermenter, ngakolunye uhlangothi, uhlobo oluthile lwe-bioreactor olusetshenziswa kakhulu ezinqubweni zokuvutshelwa. I-Fermentation inqubo ye-metabolic esebenzisa ama-microorganisms, inwevu noma amagciwane noma amagciwane, ukuguqula ushukela abe ama-acid, amagesi, noma utshwala.Ama-biofermemerters zenzelwe ukudala indawo evumelana nokukhula kwalezi zinto ezincane, ngaleyo ndlela zikhiqize izinhlobo ezahlukene ze-bioproducts njenge-ethanol, ama-organic acid, kanye nemithi.

Umehluko omkhulu

Umsebenzi:

Ama-bioreactors angasetshenziselwa izinhlobonhlobo zama-bioprococeses, kufaka phakathi isiko leseli kanye nokusabela kwe-enzyme, ngenkathi ama-FERmenters enzelwe ngqo izinqubo zokuvutshelwa.

Ukucaciswa kwe-Design:
Ama-biofermemerterszivame ukuklanywa ngezici ezithile zokuhlangabezana nezidingo zezinto ezivuthayo. Isibonelo, bangafaka izici ezifana nama-baffles ukuthuthukisa ukuxubana, amasistimu athile a-aeoration wokuvutshelwa kwe-aerobic, kanye nezinhlelo zokulawula izinga lokushisa ukuze ulondoloze izimo zokukhula kahle.

Isicelo:
Ama-bioreactors ahlukahlukene kakhulu futhi angasetshenziselwa izinhlelo ezahlukahlukene zezinsizakusebenza ezimbonini ezahlukene, kufaka phakathi amakhemikhali, ukudla kanye neziphuzo, ne-biotechnology yemvelo. Ngokuphambene, ama-FERmenter asetshenziswa ngokuyinhloko ezimbonini ezikhiqiza imikhiqizo yokuvutshelwa, njengokukhiqiza, ukukhiqizwa kwe-biofuel.

Isikali:
Kokubili ama-bioreatactors kanye nama-FERmenters aklanywa esikalini esihlukile, kusuka ekucwaningweni kwelebhu kuya ekukhiqizweni kwezimboni. Kodwa-ke, ama-FERmenters ajwayele ukuba namandla amakhulu okuhlalisana amanani amakhulu omkhiqizo akhiqizwa ngesikhathi senqubo yokuvutshelwa.

Indima ye-GMP ne-ASME-BPE ku-Fermenter Design

Ukuhambisana namazinga alawulayo kubalulekile uma kuziwa ekwakhiweni nasekukhiqizweni kweAma-Bio-Fermenters. Ku-Iven, siyaqinisekisa ukuthi ama-Fermenters ethu enzelwe ukuhambisana nemithethonqubo enhle yokukhiqiza (GMP) kanye ne-ASME-Bpe (American Society of Mechanic Onjiniyela - Izidingo ze-Bioprocessing) - Izidingo ze-Bioprocessing) - Izidingo ze-Bioprocessing) - Izidingo ze-Bioprocessing Lokhu kuzibophezela kwekhwalithi nokuphepha kubalulekile kumakhasimende ethu we-biopharmaceutical ancike kwimishini yethu yokuvutshelwa kwezimpawu ze-microbial.

-KwethuAmathangi WokuvuvukalaFaka izici ozimele, ezisebenziseka kalula futhi ezihlelekile ezingahlanganiswa kalula ezinhlelweni ezikhona. Sinikezela ngemikhumbi evumelana namazinga ahlukahlukene kazwelonke wengcindezi kazwelonke, kufaka phakathi i-ASME-U, GB150 ne-PED (Ingcebo Yezisetshenziswa). Lokhu kuguqulwa kabusha kuqinisekisa ukuthi amathangi ethu angathola uhla oluhlukahlukene lwezicelo kanye nezidingo zokulawula.

Ukwenza ngokwezifiso nokuguquguquka okuhlukahlukene

E-ITHENT, siyaqonda ukuthi ikhasimende ngalinye le-biopharmaceutical linezidingo ezihlukile. Kungakho sinikeza uhla oluphelele lwe-Fermenters lokutshala ama-microbial, kusukela ilabhorethri R & D kuya kumshayeli kanye nokukhiqizwa kwezimboni. Ama-Fermenters ethu angenziwa ngokwezifiso ezimfuneko ezithile, kufaka phakathi umthamo, osukela kumalitha ayi-5 kuya ku-30 ​​amakhiloli. Lokhu kuguquguquka kusivumela ukuthi sihlangabezane nezidingo zamagciwane e-aerobic kakhulu, njenge-Escherhia Coli nePichia Pastoris, evame ukusetshenziswa ekukhiqizweni kwe-biopharmace.

Ngokufingqa, kuyilapho womabili ama-bioreactors kanyeama-biofermemertersDlala indima ebalulekile emkhakheni we-biotechnology, asetshenziselwa izinhloso ezahlukahlukene futhi aklanywe ngemisebenzi ehlukene engqondweni. Ukuqonda lokhu kwehluka kubalulekile ekukhetheni imishini efanelekile yesicelo esithile. E-ITHENT, sizibophezele ekuhlinzekeni ama-fermenters asezingeni eliphakeme ahlangabezana nezidingo eziqinile zomkhakha we-biopharmace, aqinisekise ukuthi amakhasimende ethu angathola imiphumela emihle kakhulu ezinqubweni zokutshala ama-microbial zokutshala amagciwane. Noma ngabe usezigabeni zokuqala zocwaningo noma ukukala ukukhiqizwa kwezimboni, ubuchwepheshe bethu kanye nezixazululo ezenziwe ngezifiso kungakusiza ekutholeni ngokuzethemba kobunzima be-bioprocessing.