Eminyakeni yamuva nje, ngokusheshiswa kokuvunyelwa kwezidakamizwa, ukukhuthazwa kokuhlolwa kokuvumelana kwemithi ejwayelekile, ukuthengwa kwemithi, ukulungiswa kwesiqondisi somshuwalense wezokwelapha kanye nezinye izinqubomgomo ezintsha zemithi kuyaqhubeka nokukhuthaza ukuguqulwa nokuthuthukiswa kwemboni yemithi yaseShayina ukuze kusheshiswe, kuyilapho kuma-antibodies e-monoclonal, ama-antibodies amabili, i-ADC njengommeleli wemboni ye-biopharmaceutical ekhulayo, kuya phezulu embonini yemishini yemithi kulethe amathuba nezinselelo ezintsha. Kusukela ngo-2020, imishini yemithi yasekhaya futhi ithatha indawo enkulu yokungenisa, isabelo semakethe sanda kancane kancane. Ngakho-ke, ukuthuthukiswa kwemakethe yemishini yemithi yaseShayina eminyakeni embalwa ezayo kuzokwenzeka kanjani?

Ngokusho kwedatha yomphakathi yemishini yemithi ebhalwe ohlwini singabona ukuthi eminyakeni emibili edlule, izinkampani zemithi zaseShayina zifinyelele ukukhula okuqhubekayo, ukuchuma kwemboni iyonke kuphezulu kakhulu. Ezinye izikhungo zibikezela ukuthi ngemva kwesikhathi sobhubhane, amabhizinisi emithi yasekhaya anokuthuthukiswa kokusebenza, izinga lenkonzo elihle, ukulungiswa okulula kanye nezinye izinzuzo asengalondoloza ukukhula okuthile, ngesikhathi esifanayo, intuthuko esheshayo yemboni yemithi ye-biopharmaceutical, ama-bioreactor kanye neminye imishini kulindeleke ukuthi iqhubeke nokukhula, futhi kukhona indawo yokushintshaniswa kwamanye amazwe.

Sekukonke, amathuba embonini yemishini yemithi yaseShayina asekhona, eminyakeni embalwa ezayo izoba ochungechungeni lwezisusa ezinhle zokungenisa umjikelezo omude wokukhula. Futhi izitayela eziyinhloko zemboni noma zifaka izici ezilandelayo.

1, imakethe yasekhaya yemishini yemithi izobhekana nezinguquko ezinkulu. Njengamanje, izinkampani zemishini yemithi zaseShayina ziyimishini eyodwa kuphela, futhi isidingo semakethe sanamuhla sigxile kakhulu ekukhiqizeni okuphumelelayo, ukulawulwa kwezindleko, ukunciphisa umthelela, ngakho-ke esikhathini esizayo ukunikeza ikhambi eliphelele enanini labaphakeli kuzokhula kancane kancane. Njengenkampani yobunjiniyela bemithi enolwazi lweminyaka eyishumi, silwela ukubambisana nezidingo zamakhasimende futhi sinikeze amakhasimende amaphrojekthi obunjiniyela obuhlanganisiwe obusezingeni eliphezulu, obuchwepheshile.

2, indlela yokuthuthukisa amabhizinisi emishini yemithi izoshintsha. Esikhathini esidlule, amabhizinisi emishini yemithi aseShayina ayesemodini yokuthuthukisa enzima kakhulu, eletha izinkinga ezinjengokuchitha izinsiza, izindleko eziphakeme kanye nentuthuko ephansi iyonke yebhizinisi. Ngakho-ke, imodeli yebhizinisi yesikhathi esizayo yamabhizinisi emithi izoshintsha, kusukela ekuqondisweni kokuphatha okunzima kuya kokungakhethi. Siphinde sikhule kusukela "kumhlinzeki wesevisi yesisombululo sesistimu" kuya "ekuhlinzekweni kwemithi okuhlakaniphile".

3, imishini yezokwelapha izoba "ehlakaniphile" kakhulu. Kulezi zinsuku, ngaphansi komgomo wokunciphisa izindleko nokwandisa ukusebenza kahle, ubuhlakani sebuyindlela yokuthuthukiswa kwemboni yemishini yezokwelapha, ngokuthuthukisa, imishini yezokwelapha ingafinyelela ukulawula okuhle okuhlakaniphile nokuqapha nokulawula okukude, umqhubi angahlaziya futhi acubungule uhlelo ku-inthanethi, aqede izinyathelo noma izinqubo ezithile ngokuzimela. Njengamanje, izwe liphinde lethula izinqubomgomo zokukhuthaza nokusekela ezihlobene nokukhuthazwa kokukhiqiza okuhlakaniphile, futhi kulindeleke ukuthi ukuhlanganiswa kwemigqa yokukhiqiza ehlakaniphile kanye nemishini yokusebenza kweyunithi yemishini yezokwelapha kuzoba umkhuba ojwayelekile esikhathini esizayo. I-IVEN izophinde ithuthukise ikhono layo lokusungula izinto ezintsha esigabeni se-R&D, ukuze ikwazi ukuphendula emakethe ngesikhathi esifanele namanje ukuntuleka kobuchwepheshe obuhlakaniphile bemishini. Esigabeni sokukhiqiza ukuthuthukisa ukusebenza kahle kokukhiqiza, ukunciphisa izindleko zokukhiqiza, nokuletha amakhasimende umuzwa ongcono wokuhlangenwe nakho ekukhiqizeni imishini.

Njengamanje, amabhizinisi emithi aseShayina enkambisweni yesimanje, avame ukuthambekela emishinini ehlakaniphile neyonga amandla ephezulu, okunye kokusebenza kwemishini yendabuko ebuthakathaka, esebenzisa amandla amaningi akusadingeki. Ikusasa lamabhizinisi emishini yemithi lizoncintisana kuphela uma eqhubeka nokuthuthukisa nokuthuthukisa. Njengenkampani enolwazi lwamashumi eminyaka, i-Evon ihlinzeke ngamaphrojekthi obunjiniyela ahlanganisiwe ezitshalweni zemithi ezingaphezu kuka-30 kanye namabhizinisi emithi emhlabeni jikelele, silwela ukuhlangana nemishini yemithi ephezulu engenisiwe, ukuletha imishini yaseShayina emhlabeni, futhi ndawonye sihlinzeke ngomnikelo omncane empilweni yabantu yomhlaba wonke.